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How to Optimize Human Biology:  Where Genome Editing and Artificial Intelligence Collide

Genome editing and artificial intelligence (AI) could revolutionize medicine in the United States and globally. Though neither are new technologies, the discovery of CRISPR in genome editing and advances in deep learning for AI could finally grant clinical utility to both. The medical use of these technologies individually could result in their eventual combined use, raising new and troubling ethical, legal, and social questions. If ongoing technical challenges can be overcome, will the convergence of AI and CRISPR result in practitioners ‘optimizing’ human health? And could viewing human biology as a machine result in a willingness to optimize biology for reasons other than health alone? Given the rapid technical progress and potential benefits of genome editing and AI, answering these questions will become more pressing in the near future. Such concerns apply not only to the United States, but to the international medical community. Notably, China has demonstrated its desire to be a global leader in both genomics and AI, which could indicate the potential of these technologies to converge in China soon. What form should the international governance of these technologies take and how will it be enforced? To ensure responsible progress of genomics and AI in combination, a balance must be struck between promoting innovation and responding to ethical, social, and moral quandaries. (READ MORE)

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By Eleonore Pauwels

Published in Issues in Science and Technology, Summer 2016,

In A Dangerous Master, Wendell Wallach, a scholar at Yale University’s Interdisciplinary Center for Bioethics, tells the story of modern society’s struggle to cope with technology’s complexity and uncertainty. In the course of telling this story, Wallach questions the terms of the social contract under which we as a society, predict, weigh, and manage the potential harms and benefits that result from the adoption of emerging technologies. In urgent prose, he argues that we need different epistemic, cultural, and political approaches to adequately assess emerging technologies’ risks and their broader social impacts. Wallach promotes public deliberation as one of these approaches, which provides citizens and experts the opportunity to distinguish the technological hype from the hope, the speculation from reality, and in so doing shape their technological futures.

There is a whiff of science fiction in Wallach’s prose—maybe more fiction than science. He envisions a future where autonomous robots, designer babies, homemade pathogenic organisms, and mindclones confront our hopes, fears, and inner conflicts…

Full Book Review

Review of: A Dangerous Master: How to Keep Technology from Slipping Beyond Our Control, by Wendell Wallach. New York, NY: Basic Books, 2015, 336 pp.van-gogh-and-the-colors-of-the-night-13